ACCase dataset

 

Modeling data for the redesign of previously identified lead inhibitors of bacterial biotin carboxylase (BC) to expand the spectrum of organisms sensitive to amino-oxazole derivatives. Specifically, we constructed a large combinatorial library of antibiotic candidates, which were subsequently subjected to structure-based virtual screening against several biotin carboxylase isoforms from Gram-negative and Gram-positive species.

 
ACCase dataset