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eRepo-ORP

 
   
dataset dataset
 

Rational drug repositioning is expected to play a major role in the development of treatments for orphan diseases. eRepo-ORP is a new resource for orphan drug research built on local alignments between target sites for known drugs from DrugBank and proteins associated with rare diseases from Orphanet.

  
eRepo-ORP
If you use eRepo-ORP, please cite the following papers:
1 Govindaraj RG, Naderi M, Singha M, Lemoine J, Brylinski M. (2018) Large-scale computational drug repositioning to find treatments for rare diseases. NPJ Syst Biol Appl 4: 13.     
2 Brylinski M, Naderi M, Govindaraj RG, Lemoine J. (2018) eRepo-ORP: Exploring the opportunity space to combat orphan diseases with existing drugs. J Mol Biol 430 (15): 2266-2273.